Pollard, Daniel A.; Bergman, Casey M.; Stoye, Jens ; Celniker, Susan E.; Eisen, Michael B.: Benchmarking tools for the alignment of functional noncoding DNA. In: BMC Bioinformatics. Jg.5 H. 1. 2004
Inhalt
- Background
- Results
- Properties of noncoding DNA in Drosophila
- Estimates of divergence between taxa used in comparative genomics
- Simulating noncoding sequence evolution
- Characterization of simulation outputs
- Comparative analysis of genomic alignment tools
- Discussion
- Conclusions
- Methods
- Modelling input sequences for the simulation of Drosophila noncoding DNA
- Divergence estimates in flies, worms and mammals
- Simulating noncoding sequence divergence
- Tools for aligning noncoding DNA
- Alignment performance measures
- Authors' contributions
- Acknowledgements
- References