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West, Beate: Lipid-protein interactions in lipid membranes. 2008
Inhalt
Introduction
Membrane Lipids
Membrane Proteins
Membrane-Protein Interactions
Coarse-Graining
Present Work
Theories on Lipid-Protein Interactions
Mean Field Theory
Landau-de Gennes Theory
Elastic Theory
Elastic Theory with Local Tilt
Integral Equation Theory
Chain Packing Theory
Theory of Fluctuation-Induced Interactions
Conclusions
Coarse-Grained Model
Bilayer Model
Bilayer Characterising Quantities
Protein Model
Protein Model with Tilt
Methods
Monte Carlo Simulations
Pressure Profile
Parallelisation
Characteristics of a Pure Lipid Bilayer
Pressure Profiles
Fluctuation Spectra
Conclusions
Lipid Bilayer with One Protein in the Fluid Phase
Bilayer Deformation
Influence of the System Size on the Thickness Profile
Comparison between Different Protein Diameters
Protein with Tilt
Calculation of the Free Energy Using Thermodynamic Integration
Conclusions
Lipid Bilayer with Two Proteins in the Fluid Phase
Effective Interaction between Two Proteins
Bilayer Deformation
Comparison between Different Protein Diameters
Protein with Tilt
Conclusions
Conclusions and Outlook
System Size Dependence of the Tension Profile
Calculation of the Free Energy in the Elastic Theory
Collection of System Characteristics
Protein of Diameter p=3t
Protein of Diameter p=1t
Additional Figures
Protein of Diameter p = 1t
Protein with Tilt