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Wang, Ying: Nanomechanics of DNA-ligand interaction investigated with magnetic tweezers. 2017
Inhalt
List of publications
Introduction
Background and theory
DNA
Chemical structure
DNA conformation
Secondary structure
Superhelical form
Physical characteristics
Molecular recognition
Ligand-DNA interaction
Specific binding
Technique and theoretical models
Magnetic tweezers
Theoretical polymer models
McGhee-von Hippel model
Sample preparation and object ligands
Flow cell
DNA samples
Functionalization of lambda dsDNA
Functionalization of M13 ssDNA
MT buffer
Cu2(OAc)2
Fluorescent DNA binding dyes
YOYO-1
DAPI
DRAQ5
PicoGreen
Histones
Discussions and reprints of publications
Paper I
Papers II-IV
Paper V
Concluding discussion and outlook
References
List of abbreviations
Acknowledgments