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Haupka, Carsten ; Délepine, Baudoin; Irla, Marta; Heux, Stéphanie; Wendisch, Volker F.: Flux enforcement for fermentative production of 5-aminovalerate and glutarate by Corynebacterium glutamicum. In: Catalysts. Jg.10. 2020
Inhalt
Results
Design of the Study: Comparing Flux Enforcement with Either a Single or Two Coupling Sites
Proof of Principle: Putrescine Oxidases Oxidatively Deaminate Cadaverine in C. glutamicum
Deletion of Genes for Conversion of 5AVA to Glutarate and Change of the Microcultivation System Improved 5AVA Production
Flux Enforcement by Deletion of the l-Glutamic Acid Dehydrogenase Gene Improved Glutarate Production
Discussion
Materials and Methods
Microorganisms and Cultivation Conditions
Molecular Biology Methods
HPLC Analysis
Conclusions
References