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Gestefeld, Birte; Marsman, Jan-Bernard; Cornelissen, Frans W.: How Free-Viewing Eye Movements Can Be Used to Detect the Presence of Visual Field Defects in Glaucoma Patients. In: Frontiers in Medicine. Jg.8. 2021
Inhalt
Exploiting Naturally Occurring Eye Movements to Monitor the Occurrence of VFD
VFD Influence Eye Movements
Cross Validating Previous Methods of Analysis
Experiment 1: Monocular Eye Movements Under Free-Viewing Conditions of Glaucoma Patients Compared to Those of Normal Sighted Observers
Methods
Summary
Participants
Procedure
Stimulus Presentation and Eye Tracking
Selection of the Video Clips
Data Analysis
Fixations and Saccades in Visual Field Coordinates
Basic Eye Movement Features
Comparison of Directional Saccade Amplitudes of Glaucoma Patients and Controls
Viewing Priority
Comparison of the Spatial Distribution of Eye Movement Features in the Visual Field Between Groups
Reconstructing the VFD Based on the Spatial Distribution of Eye Movement Features in the Visual Field
Statistical Testing
Results
Basic Eye Movement Features
Comparison of Directional Saccade Amplitudes Between Patients and Controls
Viewing Priority
Spatial Distribution of Eye Movement Features in the Visual Field Used to Distinguish Between Patients and Controls
Spatial Distribution of Eye Movement Features in the Visual Field Used to Reconstruct the VFD
Correlation Between the Measured Sensitivity by the HFA and the Fixation Frequency
Experiment 2: Binocular Eye Movements Under Free-Viewing Conditions of Glaucoma Patients Compared to Those of Normal Sighted Observers
Methods
Summary
Participants
Stimulus Materials
The Integrated Visual Field (IVF)
Eye Movement Data Analysis
Fixations and Saccades in Visual Field Coordinates
Basic Eye Movement Features
Comparison of Directional Saccade Amplitudes of Glaucoma Patients and Controls
Viewing Priority
Comparison of the Spatial Distribution of Eye Movement Features in the Visual Field Between Groups
Reconstructing the VFD Based on the Spatial Distribution of Eye Movement Features in the Visual Field
Results
Basic Eye Movement Features
Comparison of Directional Saccade Amplitudes Between Patients and Controls
Viewing Priority
Spatial Distribution of Eye Movement Features in the Visual Field Used to Distinguish Between Patients and Controls
Spatial Distribution of Eye Movement Features in the Visual Field Used to Reconstruct the VFD
Discussion
Detecting a VFD Requires Monocular Viewing
Detecting a VFD Under Free-Viewing Conditions Requires Suitable Video Content
Usability of Current Eye-Tracking Technology in Elderly and Clinical Populations
Using Virtual Reality and Mobile Eye Tracking During Daily Life Activities Instead of a (Small) Screen Could Improve the Separability of Patients and Controls
VP May Correlate More Strongly With Functional Vision Than the Severity of the VFD Defined by the MD Value
Future Studies
Conclusion
Data Availability Statement
Ethics Statement
Author Contributions
Funding
Acknowledgments
Supplementary Material
References