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Kaltschmidt, Barbara; Witte, Kaya E.; Greiner, Johannes F. W.; Weissinger, Florian; Kaltschmidt, Christian: Targeting NF-κB Signaling in Cancer Stem Cells: A Narrative Review. In: Biomedicines. Jg.10 H. 2. 2022
Inhalt
Cancer and Cancer Stem Cells
Development of Cancer Stem Cells and Cancer Origin
Micro- and Macroenvironment of Cancers
Cellular Hierarchy and Cancer Stem Cell-Specific Characteristics
Influence of Tumors’ Heterogeneity on Therapy of Cancer Stem Cells
The Transcription Factor NF-B as a Target in Cancer Stem Cells
Introduction to Alternative and Classical NF-B Signaling
Systemic Therapy Targeting NF-B
Targeted Therapy of Cancer Stem Cells: An Excursion
Anti-Inflammatory Cues Acting on NF-B in Cancer Stem Cells
Conclusions: Lessons Learned for Cancer Stem Cell Therapy
References