TY - JOUR AB - The intrinsic dc conductivity of long, individual lambda phage dsDNA molecules has been investigated by ultrasensitive low current-voltage-spectroscopy (IV) under ambient conditions and controlled low humidity inert gas atmosphere on microfabricated metal-insulator-metal gap structures. We found a strong dependence of the measured conductivity on the apparent humidity, which we attribute to capillary condensation of water to the immobilized DNA molecules, giving rise to additional ionic currents. Additional IV-spectroscopy experiments under controlled argon atmosphere always revealed a significant drop in electrical conductivity to 4 × 10 -15 AV -1 µm -1, indicating almost no considerable contribution of electrical long range charge transport. DA - 2004 DO - 10.1016/j.jbiotec.2004.04.031 KW - DNA conductivity KW - Current-voltage spectroscopy KW - Microstructures LA - eng IS - 1-2 M2 - 91 PY - 2004 SN - 0168-1656 SP - 91-95 T2 - Journal of Biotechnology TI - Absence of intrinsic electric conductivity in single dsDNA molecules UR - https://nbn-resolving.org/urn:nbn:de:0070-pub-17731258 Y2 - 2024-11-21T17:44:47 ER -