TY  - JOUR
AB  - Recent developments in single molecule force spectroscopy (SMFS) allow direct observation and measurements of forces that hold protein-DNA complexes together. Furthermore, the mechanics of double-stranded (ds) DNA molecules in the presence of small binding ligands can be detected. The results elucidate molecular binding mechanisms and open the way for ultra sensitive and powerful biosensor applications.
DA  - 2004
DO  - 10.1016/j.jbiotec.2004.04.029
KW  - Optical tweezers
KW  - Single molecule force spectroscopy
KW  - Atomic force microscopy
KW  - Ligand–DNA interaction
LA  - eng
IS  - 1-2
M2  - 5
PY  - 2004
SN  - 0168-1656
SP  - 5-12
T2  - Journal of Biotechnology
TI  - Single molecule force spectroscopy on ligand-DNA complexes: from molecular binding mechanisms to biosensor applications
UR  - https://nbn-resolving.org/urn:nbn:de:0070-pub-17731486
Y2  - 2024-11-22T02:10:40
ER  -