TY  - JOUR
AB  - Molecular recognition between biotinylated bovine serum albumin and polyclonal, biotin-directed IgG antibodies has been measured directly under various buffer conditions using an atomic force microscope (AFM). It was found that even highly structured molecules such as IgG antibodies preserve their specific affinity to their antigens when probed with an AFM in the force mode. Evidence that only a very limited number (less than 10) antibody/antigen pairs contribute to the measured interaction force is given. The potential and limitations of this new approach for the measurement of individual antigen/antibody interactions, and some possible applications are discussed.
DA  - 1996
LA  - eng
IS  - 5
M2  - 2437
PY  - 1996
SP  - 2437-2441
T2  - Biophysical journal
TI  - Specific antigen/antibody interactions measured by force microscopy
UR  - https://nbn-resolving.org/urn:nbn:de:0070-bipr-438
Y2  - 2024-11-22T09:01:31
ER  -