TY  - JOUR
AB  - T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position weight matrices. The user inputs a set of such weight matrices or binding site sequences and our program matches them against the T-Reg database, which is presently built on data from the Transfac [E. Wingender (2004) In Silico Biol., 4, 55-61] and Jaspar [A. Sandelin, W. Alkema, P. Engstrom, W. W. Wasserman and B. Lenhard (2004) Nucleic Acids Res., 32, D91-D94]. Our tool delivers a detailed report on similarities between user-supplied motifs and motifs in the database. Apart from simple one-to-one relationships, T-Reg Comparator is also able to detect similarities between submatrices. In addition, we provide a user interface to a program for sequence scanning with weight matrices. Typical areas of application for T-Reg Comparator are motif and regulatory module finding and annotation of regulatory genomic regions. T-Reg Comparator is available at http://treg.molgen.mpg.de.
DA  - 2005
DO  - 10.1093/nar/gki590
LA  - eng
IS  - Web Server
M2  - W438
PY  - 2005
SN  - 0305-1048
SP  - W438-W441
T2  - Nucleic Acids Research
TI  - T-Reg Comparator: an analysis tool for the comparison of position weight matrices
UR  - https://nbn-resolving.org/urn:nbn:de:0070-pub-17736958
Y2  - 2024-11-24T02:18:26
ER  -