TY  - JOUR
AB  - Electric impulses were found to cause transient permeability changes in the membranes of vesicles storing biogenic amines. Release of catecholamines induced by electric fields (of the order of 20 kV/cm and decaying exponentially with a decay time of about 150 [mu]sec) was studied, using the chromaffin granules of bovine adrenomedullary cells as a vesicular model system. Far-UV-absorption spectroscopy was applied to determine the amount of catecholamines released from suspended vesicles. A polarization mechanism is suggested for the induction of short-lived permeability changes caused by electric fields. Such transient changes in permeability may possibly represent a part of the sequence of events leading to stimulated neurohumoral secretion.
DA  - 1972
DO  - 10.1007/BF01867861
LA  - eng
IS  - 1
M2  - 279
PY  - 1972
SN  - 0022-2631
SP  - 279-290
T2  - Journal of Membrane Biology
TI  - Permeability changes induced by electric impulses in vesicular membranes
UR  - https://nbn-resolving.org/urn:nbn:de:0070-pub-17743914
Y2  - 2024-11-22T05:16:30
ER  -