TY  - JOUR
AB  - Physico-chemical factors that determine tracer substance flux from or into sealed vesicular structures are examined. Flux amplitudes are dependent on the average volume of a vesicle, while flux rates depend on the average number of transmembrane channels per vesicle. Gating processes leading to channel opening and/or closing affect both amplitudes and rates. Averaging over inhomogeneities in vesicle size and channel density leads to an explicit expression for time-dependent tracer content. Means for experimentally determining all variable factors in this expression are discussed.
DA  - 1980
DO  - 10.1016/0022-5193(80)90304-5
KW  - Computational Biology
KW  - Mathematical Biology
KW  - Biology
LA  - eng
IS  - 4
M2  - 649
PY  - 1980
SN  - 0022-5193
SP  - 649-661
T2  - Journal of Theoretical Biology
TI  - Analysis of gated flux from or into sealed membrane fragments
UR  - https://nbn-resolving.org/urn:nbn:de:0070-pub-17744312
Y2  - 2024-11-22T01:03:42
ER  -