TY  - JOUR
AB  - Recent information obtained, mainly by recombinant cDNA technology, on structural heterogeneity of hormone and transmitter receptors, of GTP-binding proteins (G-proteins) and, especially, of G-protein-linked receptors is reviewed and the implications of structural heterogeneity for diversity of hormone and transmitter actions is discussed. For the future, three-dimensional structural analysis of membrane proteins participating in signal transmission and transduction pathways is needed in order to understand the molecular basis of allosteric regulatory mechanisms governing the interactions between these proteins including hysteretic properties and cell-cybernetic aspects.
DA  - 1991
DO  - 10.1111/j.1432-1033.1991.tb16085.x
KW  - NUCLEOTIDE REGULATORY PROTEINS
KW  - BETA-ADRENERGIC-RECEPTOR
KW  - AMINO-ACID SEQUENCE
KW  - NICOTINIC ACETYLCHOLINE-RECEPTOR
KW  - MUSCARINIC K+-CHANNEL
LA  - eng
IS  - 1
M2  - 1
PY  - 1991
SN  - 0014-2956
SP  - 1-15
T2  - European Journal of Biochemistry
TI  - Structural heterogeneity of membrane receptors and GTP-binding proteins and its functional consequences for signal transduction
UR  - https://nbn-resolving.org/urn:nbn:de:0070-pub-17745609
Y2  - 2024-11-22T04:56:29
ER  -