TY - JOUR AB - We have demonstrated the synthesis of a 74,000-dalton protein (74K protein) in African green monkey kidney cells infected with simian virus (SV)40. The 74K protein was detected late during the lytic cycle. Its synthesis was inhibited by arabinosyl cytosine as was the synthesis of the capsid proteins. Monospecific antibodies raised against VP1 and VP3 precipitated the structural proteins and the 74K protein. The 74K protein was not found in purified virions. Tryptic peptide analysis demonstrated that the 74K protein shares methionine- and serine-containing peptides with VP1 and VP3 and thus is structurally related to the capsid proteins. DA - 1983 DO - 10.1002/jcb.240220402 KW - structural proteins KW - tryptic peptide analysis KW - immunoprecipitation KW - SV40 LA - eng IS - 4 M2 - 197 PY - 1983 SN - 0730-2312 SP - 197-207 T2 - Journal of Cellular Biochemistry TI - A simian virus 40-encoded protein of M r 74,000 daltons is structurally related to the capsid proteins of the virus UR - https://nbn-resolving.org/urn:nbn:de:0070-pub-17785692 Y2 - 2024-11-22T06:24:44 ER -