TY - THES AB - The cryptophycins are cyclic depsipeptides with tumour-selective cytotoxicity. A short and efficient synthesis of the pharmacologically most interesting representative (cryptophycin 52) was developed and used for the synthesis of analogues. Moreover, the accessibility of diastereomers of the unit A building block was investigated. DA - 2008 KW - Cryptophycine , Totalsynthese , Tumorhemmstoff , , Antitumour compound , Total synthesis , Medicinal chemistry LA - ger PY - 2008 TI - Synthese von Cryptophycinen für SAR-Studien UR - https://nbn-resolving.org/urn:nbn:de:hbz:361-13019 Y2 - 2024-11-26T06:16:34 ER -