TY  - THES
AB  - A rapid development of novel and more efficient amination methods has been recorded during the past decade, mostly regarding the electrophilic amination. There are only few efficient methods for reagent-controlled stereoselective electrophilic amination compared to those based on chiral substrates or chiral catalysts. An effective stereoselective amination reagent allows greater method flexibility, due to the high availability of prochiral nucleophilic substrates. In the present work the reactivity of three types of enantiomerically pure electrophilic amination reagents (N-lithiated N-pinenyl hydroxylamines, [alpha]-chloronitroso camphor and mannofuranose derivatives, and 1-deoxy-2,3:5,6-di-O-isopropylidene-1-nitro-[alpha]-D-mannofuranose) towards carbon nucleophiles (enolates and allyl organometallic compounds) was investigated, with the aim to provide a valuable method for the stereoselective synthesis of [alpha]-amino ketones and [alpha]-amino acids.
DA  - 2002
KW  - Carbanion , Elektrophile Aminierung , Asymmetrische Reaktion , Reagenz , Chirale Verbindungen , Chemische Synthese , Enantioselektivität ,  , Electrophilic amination , Stereoselective synthesis , Amino acids , Nitrenoid
LA  - eng
PY  - 2002
TI  - Studies towards the stereoselective electrophilic amination of carbanions
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:361-2317
Y2  - 2024-11-22T11:36:29
ER  -