TY  - THES
AB  - The vast majority of microbial species found in nature has yet to be grown in pure culture, turning metagenomics and – more recently – single cell genomics into indispensable methods to study the microbial dark matter.<br /><br />

I developed, applied, and benchmarked genome assembly protocols for single cell and metagenome sequencing data to access microbial dark matter genomes.<br /><br />

In the first part of my thesis, I propose new algorithms that naturally exploit the complementary nature of single cells and metagenomes to improve the quality of single cell assemblies.<br /><br />

In the second part, I apply advanced metagenome assembly and binning techniques to untangle genomes from metagenomes, eventually reconstructing hundreds of near-complete genomes of process-relevant community members in the biogas microbiome.
DA  - 2016
LA  - eng
PY  - 2016
TI  - Assembling the microbial dark matter
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:361-29067436
Y2  - 2024-11-24T12:53:13
ER  -