TY  - JOUR
AB  - Phytochemical investigation of the ethyl acetate extract of the roots of Aloe megalacantha led to the isolation of four new natural products—1,8-dimethoxynepodinol (1), aloesaponarin III (2), 10-O-methylchrysalodin (3) and methyl-26-O-feruloyl-oxyhexacosanate (4)—along with ten known compounds. All purified metabolites were characterized by NMR, mass spectrometric analyses and comparison with literature data. The isolates were evaluated for their cytotoxic activity against a human cervix carcinoma cell line KB-3-1 and some of them exhibited good activity, with aloesaponarin II (IC50 = 0.98 µM) being the most active compound.
DA  - 2017
DO  - 10.3390/molecules22071136
KW  - Asphodelaceae
KW  - Aloe megalacantha
KW  - roots
KW  - quinone
KW  - anthraquinone
KW  - cytotoxicity
LA  - eng
IS  - 7
PY  - 2017
SN  - 1420-3049
T2  - Molecules
TI  - Cytotoxic Compounds from Aloe megalacantha
UR  - https://nbn-resolving.org/urn:nbn:de:0070-pub-29126997
Y2  - 2024-12-04T08:48:23
ER  -