TY  - GEN
AB  - We present a new whole-genome based approach to infer large-scale phylogenies
that is alignment- and reference-free. In contrast to other methods, it does
not rely on pairwise comparisons to determine distances to infer edges in a
tree. Instead, a colored de-Bruijn graph is constructed, and information on
common subsequences is extracted to infer phylogenetic splits. Application to
different datasets confirms robustness of the approach. A comparison to other
state-of-the-art whole-genome based methods indicates comparable or higher
accuracy and efficiency.
DA  - 2019
LA  - eng
PY  - 2019
TI  - Alignment- and reference-free phylogenomics with colored de-Bruijn  graphs
UR  - https://nbn-resolving.org/urn:nbn:de:0070-pub-29356042
Y2  - 2024-11-21T20:47:30
ER  -