TY - JOUR AB - Current super-resolution structured illumination microscopes (SR-SIM) utilize relatively expensive electro-optic components and free-space optics, resulting in large setups. Moreover, high power laser sources are required to compensate for the losses associated with generating the illumination pattern by diffractive optics. Here, we present a highly compact and flexible 2D SR-SIM microscope based on all-fiber optic components (fiberSIM). Fiber-splitters deliver the laser light to the sample resulting in the interference illumination pattern. A microelectromechanical systems (MEMS) based fiber switch performs rapid pattern rotation. The pattern phase shift is achieved by the spatial displacement of one arm of the fiber interferometer using a piezoelectric crystal. Compared with existing methods, fiberSIM is highly compact and significantly reduces the SR-SIM component cost while achieving comparable results, thus providing a route to making SR-SIM technology accessible to even more laboratories in the life sciences. (C) 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement DA - 2021 DO - 10.1364/OE.420592 LA - eng IS - 8 M2 - 11833 PY - 2021 SP - 11833-11844 T2 - Optics Express TI - Highly compact and cost-effective 2-beam super-resolution structured illumination microscope based on all-fiber optic components UR - https://nbn-resolving.org/urn:nbn:de:0070-pub-29551201 Y2 - 2024-11-25T03:51:52 ER -