TY  - JOUR
AB  - Corynebacterium glutamicum is used for the million-ton-scale production of amino
acids. Valorization of sidestreams from agri- and aqua-culture has focused on the
production of biofuels and carboxylic acids. Nitrogen present in various amounts in
sidestreams may be valuable for the production of amines, amino acids and other
nitrogenous compounds. Metabolic engineering of C. glutamicum for valorization of
agri- and aqua-culture sidestreams addresses to bridge this gap. The product portfolio
accessible via C. glutamicum fermentation primarily features amino acids and diamines
for large-volume markets in addition to various specialty amines. On the one hand, this
review covers metabolic engineering of C. glutamicum to efficiently utilize components
of various sidestreams. On the other hand, examples of the design and implementation
of synthetic pathways not present in native metabolism to produce sought after
nitrogenous compounds will be provided. Perspectives and challenges of this concept
will be discussed
DA  - 2022
DO  - 10.3389/fmicb.2022.835131
LA  - eng
PY  - 2022
T2  - Frontiers in Microbiology
TI  - Metabolic Engineering for Valorization of Agri-and Aqua-culture Sidestreams for Production of Nitrogenous Compounds by Corynebacterium glutamicum
UR  - https://nbn-resolving.org/urn:nbn:de:0070-pub-29605549
Y2  - 2024-11-25T08:29:52
ER  -