Unlike European Schools of Public Health, whose development was primarily influenced by the medical profession and was linked to the healthcare system, North American Schools of Public Health operate as independent academic institutions engaged in research and education of Public Health specialists. While Public Health has been recognised as a distinctive profession in USA and Canada for almost a century, in many European countries it is not recognized as such and, accordingly, there are no well-defined job positions for graduates. Similarities and differences between the European and American Schools of Public Health are reviewed and the importance of classification of core competences, responsibilities and scope of knowledge required for Public Health practice was pointed out as a prerequisite for accreditation of study curricula. For the professionalization of Public Health in Europe further efforts are needed.