Armitage, Sophie A. O.; Kurtz, Joachim; Brites, Daniela ; Dong, Yuemei ; Du Pasquier, Louis ; Wang, Han-Ching: 'Dscam1' in Pancrustacean Immunity: Current Status and a Look to the Future
Inhalt
- One Protein, Two Roles?
- Dscam Diversity in Arthropods
- Dscam1 and Immune Defense in Pancrustaceans
- Our Aims
- Question 1. Looking Back at 10 years of Research on a Potential Immune Function of Dscam1, Do You Think That Dscam1 Has a Role in Pancrustacean Immunity?
- Daniela Brites and Louis Du Pasquier
- Yuemei Dong
- Han-Ching Wang
- Sophie A. O. Armitage and Joachim Kurtz
- Question 2. Dscam1 Was Hypothesized to Produce the Large Number of Variable Receptors Needed for Specificity in the Immune Response, in Some Ways Analogous to Antibodies in Vertebrates. Do You Think That Dscam1 Is Indeed the Equivalent of Antibodies As Specific Immune Receptors?
- Question 3. Next to Specificity, Remembering Is a Key Aspect of Immune Memory. Could This Be Achieved with Dscam1?
- Daniela Brites and Louis Du Pasquier
- Yuemei Dong
- Han-Ching Wang
- Sophie A. O. Armitage and Joachim Kurtz
- Question 4. What Alternatives Are There to an Antibody-Like Function of Dscam1 in Pancrustacean Immune Systems?
- Question 5. What Is the Meaning of Dscam1 Genetic Diversity?
- Question 6. What Was the Main Factor Driving the Evolution of Diversity in Dscam1—The Nervous or Immune System or Even Something Else?
- Question 7. What Are the Future Perspectives for Studies on Dscam1 in Immunity? (Including What Essential Experiments or Approaches Are Missing That Would Help Our Understanding of Dscam1 in Immunity?)
- Author Contributions
- Acknowledgments
- Funding
- References