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Lüttjohann, Annika ; Pape, Hans-Christian: Regional specificity of cortico-thalamic coupling strength and directionality during waxing and waning of spike and wave discharges
Inhalt
Animals.
Stereotactic surgery and electrophysiological recordings.
Histology.
Data analysis and statistics.
Figure 1 Exemplary recording traces showing simultaneous LFP and unit recordings in SCtx and VPM during six seconds pre-SWD -> SWD (left panel) and SWD -> post-SWD (middle panel) transition periods.
Results
Electrophysiological characteristics of SWDs in defined thalamic nuclei and somatosensory cortex.
Cortico-thalamic dynamics in coupling strength and coupling direction.
Figure 2 Coupling dynamics between SCtx and VPM along transition periods characterizing SWD on- and offset.
Figure 3 Coupling dynamics between SCtx and PO along transition periods characterizing SWD on- and offset.
Figure 4 Coupling dynamics between SCtx and RTN along transition periods characterizing SWD on- and offset.
Intrathalamic dynamics in coupling strength and coupling direction.
Discussion
Acknowledgements