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Johnen, Andreas ; Bertoux, Maxime: Psychological and Cognitive Markers of Behavioral Variant Frontotemporal Dementia–A Clinical Neuropsychologist's View on Diagnostic Criteria and Beyon [...]
Inhalt
The Clinical Diagnostic Criteria for bvFTD
Sources of Information to Evaluate the FTDC Criteria in a Clinical Setting
Clinical-Neurological Examination
Patient Anamnesis and Clinical Observations of Patients
Caregiver Interviews and Standardized Questionnaires
Behavioral and Psychological Symptoms of the Current FTDC Criteria
Behavioral Disinhibition
Apathy and Inertia
Loss of Empathy or Sympathy
Perserverative, Stereotyped, or Compulsive/ Ritualistic Behaviors
Eating Behavior and Dietary Changes
Cognitive Dysfunctions in bvFTD
Executive Functions
Response Inhibition and Cognitive Flexibility
Abstract Reasoning
Initiation
Strategic Reasoning (Multitasking, Planning Abilities)
Working Memory and Attentional Control
Memory, Episodic Future Thinking, and Spatial/Topographical Navigation
Visuo-Spatial and Visuo-Construction Abilities
Summary of Cognitive Dysfunctions in bvFTD as Stated in the FTDC Criteria
Promising Cognitive and Psychological Markers for bvFTD Beyond Current Diagnostic Criteria
Social and Affective Cognition
Theory of Mind, Mental State-Inference
Emotion Recognition, Responding, and Expressiveness
Self-Related Representations and Agency
Social Norms and Rules Processing Deficits
Reward Processing Deficit and Affective Decision Making
Symptomatic Behaviors of bvFTD and Social/Affective Cognition Impairments
Clinical Assessment of Social and Affective Cognition
Apraxia
Apraxia and Impairment of Praxis Domains in Neurodegenerative Diseases
Neural Substrates of Praxis Impairments
Clinical Assessment of Praxis Impairments
Interoception and its Potential Links With Social Cognition, Apraxia, and Behavioral Symptoms of bvFTD
Conclusion, Challenges, and Outlook
Author Contributions
Funding
References