Boström, Kim ; Boström, Kim Joris ; Boström, K. J. ; Lussanet, Marc H. E. de ; Weiß, Thomas ; Weiß, T. ; Puta, Christian ; Wagner, Heiko: A computational model unifies apparently contradictory findings concerning phantom pain
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- Figure 1 Schematic representation of two variations of the computational model: (a) Model variation A involving an integrated cortical map receiving input from both tactile and nociceptive channels.
- Table 1 Values of the model parameters on the three conditions PRE, NOPAIN, and PAIN, for the tactile and nociceptive channels (“Tact” and “Noci”). On the PRE condition, all channels share the same values (“All fingers”). On the NOPAIN and PAIN conditions, only those channels originating in the amputated finger are modified with respect to the PRE condition, and only those are indicated here (“Amputated finger”). Blank fields correspond to values that are unch
- Figure 2 Representative example of the cortical map in model variation A, after the training phase with the parameters from the three conditions PRE (before amputation), NOPAIN (after amputation of the middle finger, without SCA enhancement), and PAIN (after amputation, followed by strong SCA enhancement).
- Figure 3 The same representative simulation of model variation A as in Figure 2, showing the activity of the integrative cortical map, summed over the probing phase (movement of the existing or phantom middle finger) after training with the parameters according to the conditions PRE, NOPAIN, and PAIN.
- Figure 4 Central tactile (white), nociceptive (dark gray), and total (light gray) activity from sensory channels originating in the (amputated) middle finger.
- Figure 5 Cortical map reorganization after the training phase, measured by the change in distance between the centroids of the cortical representations of index finger and ring finger, measured in cell units (1 unit = distance between the centers of two neighboring cells on the cortical map), relative to the value on the PRE condition.
- Figure 6 Input-output relation of the linear gates implemented in the model.
- References