Günl, Franziska; Mecate-Zambrano, Angeles ; Rehländer, Selina; Hinse, Saskia; Ludwig, Stephan ; Brunotte, Linda: Shooting at a Moving Target—Effectiveness and Emerging Challenges for SARS-CoV-2 Vaccine Development
Inhalt
- Clinical Evaluation and Real-World Effectiveness of First-Generation SARS-CoV-2 Vaccines
- mRNA Vaccines
- BNT162b2 (Biontech/Pfizer)
- mRNA-1273 (Moderna)
- CVnCoV (CureVac)
- Effectiveness of mRNA Vaccines against Variants
- Adverse Effects Associated with mRNA Vaccination
- Adenovirus-Based Vaccines
- AZD1222 (AstraZeneca)
- Sputnik V (Gamaleya Institute)
- Ad26.COV.S (Janssen/Johnson & Johnson)
- Ad5-nCoV (CanSino Biological Inc.)
- Effectiveness of Adenovirus-Based Vaccines against Variants
- Adverse Effects Associated with Adenovirus-Based Vaccines
- Real-World Adaptions: Heterologous Vaccination
- Inactivated Virus and Recombinant Protein Vaccines
- Real-World Needs and Expansion of Clinical Investigations to Vulnerable Groups
- Vaccination of Pregnant Women
- Vaccination of Children Aged <15 Years
- Mortality in Aged Care Facilities (ACF)
- Real-World Challenges for SARS-CoV-2 Vaccines
- Conclusions
- References