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Jürgens, Franziska M.; Behrens, Matthias ; Humpf, Hans-Ulrich ; Robledo, Sara M.; Schmidt, Thomas J.: In Vitro Metabolism of Helenalin Acetate and 11α,13-Dihydrohelenalin Acetate: Natural Sesquiterpene Lactones from Arnica
Inhalt
Results and Discussion
Phase I Metabolism
Phase II Metabolism (Glucuronidation and Sulfation)
Combined Phase I and Phase II Metabolism
Materials and Methods
Chemicals and Materials
Incubation with Liver Microsomes or Liver Cytosol
Phase I Metabolism
Phase II Metabolism
UHPLC-QqTOF MS Analysis
Conclusions
References