Flammang, Isabelle; Reese, Moritz ; Yang, Zixuan ; Eble, Johannes A. ; Dhayat, Sameer: Tumor-Suppressive miR-192-5p Has Prognostic Value in Pancreatic Ductal Adenocarcinoma
Inhalt
- Results
- Expression of miR-192-5p and EMT-Related Proteins in Tumor Cells of PDAC
- Transient Transfection of PDAC Cells with miR-192-5p Mimic
- Clinicopathological Patient Data
- Expression of miR-192-5p in Tumoral and Peritumoral Tissue
- Expression of Epithelial and Mesenchymal Markers in Pancreatic Tissue
- Expression of miR-192-5p in Blood Serum and Serum Exosomes
- Diagnostic Analysis of Tissue and Circulating miR-192-5p
- Prognostic Value of Tissue and Circulating miR-192-5p
- Discussion
- Materials and Methods
- Cell Culture and Transient Transfection
- Western Blotting
- Patients
- Collection of Tissue, Blood Serum, and Serum Exosomes
- Detection of Serum Exosomes by Scanning Electron Microscopy
- Isolation and Quantification of RNA
- Quantification of miR-192-5p-Expression by RT-qRT-PCR
- Tissue Microarray and Immunohistochemistry
- Statistics
- Conclusions
- References