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Rumpf, Christine; Lange, Jonas ; Schwartbeck, Bianca ; Waschkau, Bianca ; Kahl, Barbara C.: Staphylococcus aureus and Cystic Fibrosis—A Close Relationship. What Can We Learn from Sequencing Studies?
Inhalt
Adaptation to CF Airways
Clinical Impact
S. aureus—Fundamentals of Pathogenicity
S. aureus Virulence Genome
Role of Agr in Virulence Gene Regulation Via Quorum Sensing
Role of Horizontal Gene Transfer in the Spread of Virulence Genes
Impact of Varying Genotypes and Single Genes on S. aureus Pathogenicity
Genotyping of S. aureus in Cystic Fibrosis
Adaptation of S. aureus towards Persistence in Cystic Fibrosis Using WGS
S. aureus Population Dynamics in CF
MRSA in Cystic Fibrosis—Antibiotic Resistance, Persistence and Patho-Adaptation
Biofilm Formation—An Adaptive Mechanism of S. aureus in Cystic Fibrosis
Summary and Conclusions
References