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Keller, Christian W.; Pawlitzki, Marc ; Wiendl, Heinz ; Wiendl, H. ; Lünemann, Jan: Fc-Receptor Targeted Therapies for the Treatment of Myasthenia gravis
Inhalt
MG Pathophysiology
Autoantibody Specificities in MG
Anti-AChR
Anti-MuSK
Anti-LRP4
Others
Clinical Spectrum of MG
Current Immunotherapy of MG
Fc-Receptor Biology in the Pathogenesis of MG
Targeting Fc Receptor Functions in MG
rFc Multimers
FcR-Targeting Agents
FcRn-Targeting Therapeutics
New FcR-Targeting Therapies: Evidence from Clinical Trials
Fc- and FcR-Targeted Therapies in MG
Nipocalimab
Rozanolixizumab
RVT-1401
Efgartigimod
Differential Affinity of Therapeutical Complement Inhibitors to FcRn
Conclusions and Outlook
References