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Wächter, Hannah ; Yörük, Erdal ; Becker, Karsten ; Görlich, Dennis ; Kahl, Barbara C.: Correlations of Host and Bacterial Characteristics with Clinical Parameters and Survival in Staphylococcus aureus Bacteremia
Inhalt
Materials and Methods
Study Design
Clinical Data
Administered Antimicrobial Therapy
Phenotypic Characterization of Isolates
Biofilm Assay
Nuclease Assay
spa Typing
Analysis of Methicillin Resistance, agr Type and Prevalence of Toxin Genes
Statistical Analyses
Ethics Statement
Results
Study Cohort and Clinical Data
Administered Antimicrobial Therapy
Characterization of Isolates
Factors with an Impact on Survival and Mortality
Host-Related Factors
Pathogen-Related Factors
Clinical Factors
Factors with an Impact on Clinical Parameters and Treatment
Host-Related Factors
Pathogen-Related Factors
Host-Pathogen Interactions
Correlations between Pathogen Features
Discussion
Demographic and Clinical Data
Administered Antimicrobial Therapy
Colony Size and Hemolysis Activity
Biofilm
Nuclease
Clonality
Methicillin Resistance
agr Type and Toxin Gene Prevalence
Study Limitations and Strengths
Conclusions
References