TY  - JOUR
AB  - The amino alcohol serinol (2-amino-1,3-propanediol) has become a common intermediate for several chemical processes. Since the 1940s serinol was used as precursor for synthesis of synthetic antibiotics (chloramphenicol). In the last years, new scopes of applications were discovered. Serinol is used for X-ray contrast agents, pharmaceuticals or for chemical sphingosine/ceramide synthesis. It can either be obtained by chemical processes based on 2-nitro-1,3-propanediol, dihydroxyacetone and ammonia, dihydroxyacetone oxime or 5-amino-1,3- dioxane, or biotechnological application of amino alcohol dehydrogenases (AMDH) or transaminases. This review provides a survey of synthesis, properties and applications for serinol.
AU  - Andreeßen, Björn
AU  - Steinbüchel, Alexander
AU  - Steinbüchel, A.
DA  - 2011-06-13
DO  - 10.1186/2191-0855-1-12
KW  - 2-Amino-1, 3-propanediol, Amino alcohol, Serinol
LA  - eng
N1  - Finanziert durch den Open-Access-Publikationsfonds 2011/2012 der Deutschen Forschungsgemeinschaft (DFG) und der Westfälischen Wilhelms-Universität Münster (WWU Münster).
N1  - AMB Express 1 (2011) 12
N1  - Die folgenden Lizenzbestimmungen sind mit dieser Ressource verbunden:
Creative Commons Lizenz (CC BY 2.0)
http://creativecommons.org/licenses/by/2.0/
PY  - 2011-06-13
TI  - Serinol: small molecule - big impact
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-05329435744
Y2  - 2024-11-22T06:07:46
ER  -