TY  - JOUR
AB  - In continuation of earlier work on the detection of δ-aminolevulinic acid (ALA)-induced protoporphyrin IX (PPIX) in blood and serum both the extraction method and the analysis were improved considerably. Liquid chromatography (LC) analysis was transferred from capillary equipment to an analytical workflow reducing the experiment time from several hours to 10 min. These promising results enable LC coupling to modern mass spectrometers which boosts the sensitivity about 100-fold.
AU  - Peters, Insa
AU  - König, Simone
DA  - 2019-12
KW  - Protoporphyrin
KW  - MRM
KW  - Glioblastoma
KW  - Serum
KW  - Chromatographie
KW  - glioblastoma
KW  - serum
KW  - chromatography
LA  - eng
IS  - Mercator Journal of Biomolecular Analysis
M2  - 6
PY  - 2019-12
SP  - 6-9
T2  - Mercator Journal of Biomolecular Analysis
TI  - Extraction of δ-aminolevulinic acid-induced protoporphyrin IX from blood and serum and measurement using analytical chromatography coupled to mass spectrometry
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-12189602979
Y2  - 2024-11-22T02:10:48
ER  -