TY  - JOUR
AB  - Pruritus in autoimmune and inflammatory dermatoses is a common symptom that can be severe and affect the quality of life of patients. In some diseases, pruritus is related to disorders activity and severity or may occur independent of the disease. Despite the high prevalence, the symptom is still underrated and there are only a few trials investigating the efficacy of drugs for disease-specific pruritus. In this review, the characteristics and possible pathomechanisms of pruritus in various dermatoses like autoimmune bullous diseases, connective tissue diseases as well as autoimmune-associated dermatoses (atopic dermatitis, psoriasis vulgaris) is illustrated. Additionally, studies analyzing the antipruritic treatment are discussed. Summarizing, the prevalence of pruritus in these diseases demonstrates the importance for symptom recognition and the need for an efficient antipruritic therapy.
AU  - Zeidler, Claudia
AU  - Pereira, Manuel P.
AU  - Huet, Flavien
AU  - Misery, Laurent
AU  - Steinbrink, Kerstin
AU  - Ständer, Sonja
DA  - 2019-06-21
DO  - 10.3389/fimmu.2019.01303
KW  - itch
KW  - pruritus
KW  - psoriasis
KW  - atopic dermatitis
KW  - IL31
KW  - substance P
KW  - bullous pemphigoid
LA  - eng
N1  - Frontiers in Immunology 10 (2019) 1303, 1-8
N1  - Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
PY  - 2019-06-21
TI  - Pruritus in Autoimmune and Inflammatory Dermatoses
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-40189519703
Y2  - 2024-11-21T23:35:01
ER  -