TY - JOUR AB - OBJECTIVE: Whereas research has demonstrated the efficacy of cognitive restructuring (CR) for obsessive-compulsive disorder (OCD), little is known about the efficacy of specific metacognitive interventions such as detached mindfulness (DM). Therefore, this study compared the efficacy of CR and DM as stand-alone interventions. DESIGN: We conducted a randomized waitlist-controlled trial. n = 43 participants were randomly assigned to either DM or CR. Out of those participants, n = 21 participants had been previously assigned to a two-week waitlist condition. MATERIAL AND METHODS: In both conditions, treatment comprised four double sessions within two weeks. Assessment took place at baseline (Pre1), after treatment (Post) and four weeks after the end of treatment (FU). There was a second baseline assessment (Pre2) in the waitlist group. Independent evaluators were blinded concerning the active condition. Adherence and competence ratings for the two therapists were obtained from an independent rater. RESULTS: 40 patients completed the treatment. Two patients dropped out because of exacerbated depression. There were no further adverse events. Both CR and DM were shown to be superior to waitlist and equally effective at reducing OCD symptoms from pre to post assessment as measured with the Y-BOCS (CR: d = 1.67, DM: d = 1.55). In each of the two treatment conditions, eight patients (40%) exhibited a clinical significant change at post assessment. CONCLUSIONS: The results of this clinical trial suggest the potential efficacy of DM as a stand-alone intervention for OCD, however, our findings need to be interpreted with caution. Results indicate that both CR and DM should be considered as possible alternative treatments for OCD, whereas the working mechanisms of DM have yet to be elucidated. AU - Rupp, Christian AU - Falke, Charlotte AU - Doebler, Philipp AU - Andor, Fabian AU - Schneider, Fabian AU - Buhlmann, Ulrike DA - 2019-03-20 DO - 10.1371/journal.pone.0213895 LA - eng N1 - PLoS ONE 14 (2019) 3, e0213895, 1-19 N1 - Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster). N1 - This trial was funded by the Christoph-Dornier-Foundation, which is a non-profit organization for the promotion of clinical psychology (https://www.christoph-dornierstiftung.de/). Financial funding was part of the PhD scholarship awarded by the Christoph-Dornier-Foundation to Christian Rupp and Charlotte Jürgens. PY - 2019-03-20 TI - A randomized waitlist-controlled trial comparing detached mindfulness and cognitive restructuring in obsessive-compulsive disorder UR - https://nbn-resolving.org/urn:nbn:de:hbz:6-02129583890 Y2 - 2024-12-26T19:25:37 ER -