TY  - JOUR
AB  - We report on a rare case of a laryngeal carcinoma arising in a multifocal pharyngolaryngeal oncocytic papillary cystadenoma (OPC). The disease of a 63-year-old man is well documented by computed and positron emission tomography, histology, and electron microscopy. We could show that an OPC can even develop in the pharynx. The coexistence of both tumors makes this a challenging diagnosis for pathologists. Treated by surgery and radiotherapy, both lesions dissolved. Based on the literature available, we discuss the theory that the laryngeal carcinoma might be the result of a true metaplasia facilitated by chronic irritation and recommend a regular follow-up for OPC too. As in benign oncocytic lesions, we could show that the detection of numerous mitochondria is a diagnostic indicator for malignant variants as well.
AU  - Stenner, Markus
AU  - Müller, Klaus-Michael
AU  - Müller, K.-M.
AU  - Koopmann, Mario
AU  - Rudack, Claudia
DA  - 2014-09
DO  - doi:10.1097/MD.0000000000000070
LA  - eng
N1  - Medicine 93 (2014) 12, 1-4, p e70
N1  - Finanziert durch den Open-Access-Publikationsfonds 2014/2015 der Deutschen Forschungsgemeinschaft (DFG) und der Westfälischen Wilhelms-Universität Münster (WWU Münster).
PY  - 2014-09
SN  - 0025-7974
TI  - Squamous Cell Carcinoma of the Larynx Arising in Multifocal Pharyngolaryngeal Oncocytic Papillary Cystadenoma: A Case Report and Review of the Literature
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-81319386250
Y2  - 2024-11-22T04:57:28
ER  -