TY  - JOUR
AB  - In the present work, we report two cases of monozygotic twins who developed prolonged apnea during electroconvulsive therapy (ECT) as a complication of anesthesia. In both cases, prolonged action of succinylcholine caused by a butyrylcholinesterase (BCHE) deficiency was confirmed by means of the dibucaine number test. In both cases, genetic analysis using the polymerase chain reaction revealed haplotype combined A and K variant mutations of the BCHE gene, both in the heterozygous form. These data show the potential risk of BCHE deficiency as a complication of anesthesia during ECT, and in particular underline the possible genetic contribution within a complex pathogenetic model.
AU  - Zavorotnyy, Maxim
AU  - Zwanzger, Peter M.
DA  - 2011-11-03
DO  - 10.1186/1744-859X-10-30
LA  - eng
N1  - Finanziert durch den Open-Access-Publikationsfonds 2011/2012 der Deutschen Forschungsgemeinschaft (DFG) und der Westfälischen Wilhelms-Universität Münster (WWU Münster).
N1  - Annals of General Psychiatry 10 (2011) 30
PY  - 2011-11-03
TI  - Prolonged apnea during electroconvulsive therapy in monozygotic twins: case reports
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-67389411374
Y2  - 2024-11-24T06:29:05
ER  -