TY  - JOUR
AB  - Background: To overcome flow and electrocardiogram-trigger artifacts in cardiovascular magnetic resonance (CMR), we have implemented a cardiac and respiratory self-gated cine ultra-short echo time (UTE) sequence. We have assessed its performance in healthy mice by comparing the results with those obtained with a self-gated cine fast low angle shot (FLASH) sequence and with echocardiography. Methods: 2D self-gated cine UTE (TE/TR = 314 μs/6.2 ms, resolution: 129 × 129 μm, scan time per slice: 5 min 5 sec) and self-gated cine FLASH (TE/TR = 3 ms/6.2 ms, resolution: 129 × 129 μm, scan time per slice: 4 min 49 sec) images were acquired at 9.4 T. Volume of the left and right ventricular (LV, RV) myocardium as well as the end-diastolic and -systolic volume was segmented manually in MR images and myocardial mass, stroke volume (SV), ejection fraction (EF) and cardiac output (CO) were determined. Statistical differences were analyzed by using Student t test and Bland-Altman analyses. Results: Self-gated cine UTE provided high quality images with high contrast-to-noise ratio (CNR) also for the RV myocardium (CNRblood-myocardium = 25.5 ± 7.8). Compared to cine FLASH, susceptibility, motion, and flow artifacts were considerably reduced due to the short TE of 314 μs. The aortic valve was clearly discernible over the entire cardiac cycle. Myocardial mass, SV, EF and CO determined by self-gated UTE were identical to the values measured with self-gated FLASH and showed good agreement to the results obtained by echocardiography. Conclusions: Self-gated UTE allows for robust measurement of cardiac parameters of diagnostic interest. Image quality is superior to self-gated FLASH, rendering the method a powerful alternative for the assessment of cardiac function at high magnetic fields.
AU  - Hörr, Verena
AU  - Nagelmann, Nina
AU  - Nauerth, Arno
AU  - Kuhlmann, Michael Theodor
AU  - Stypmann, Jörg
AU  - Faber, Cornelius
DA  - 2013-07-04
DO  - 10.1186/1532-429X-15-59
KW  - High magnetic field
KW  - Flow artifacts
KW  - Cardiovascular magnetic resonance
KW  - Retrospective gating
KW  - Self-gated cine UTE
LA  - eng
N1  - Hoerr, Verene; Nagelmann, Nina; Nauerth, Arno; Kuhlmann, Michael T.; Stypmann, Jörg; Faber, Cornelius: Cardiac-respiratory self-gated cine ultra-short echo time (UTE) cardiovascular magnetic resonance for assessment of functional cardiac parameters at high magnetic fields. Journal of Cardiovascular Magnetic Resonance; 213, Vol. 15, 59.
http://dx.doi.org/doi:10.1186/1532-429X-15-59
PY  - 2013-07-04
TI  - Cardiac-respiratory self-gated cine ultra-short echo time (UTE) cardiovascular magnetic resonance for assessment of functional cardiac parameters at high magnetic fields
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-94309668559
Y2  - 2024-11-24T00:17:18
ER  -