TY  - JOUR
AB  - Background. Transcatheter aortic valve implantation (TAVI) is widely used in high risk patients (pts) with aortic stenosis. Underlying chronic kidney disease implicates a high risk of postprocedural acute kidney injury (AKI).We analyzed its occurrence, impact on hospital stay, and mortality. Methods. 150 consecutive pts underwent TAVI in our institution (mean age 81±7 years; logistic EuroSCORE 24±15%). AKI definition was a creatinine rise of 26.5 μmol/L or more within 48 hours postprocedural. Ten patients on chronic hemodialysis were excluded. Results. AKI occurred in 28 pts (20%). Baseline creatinine was higher in AKI pts (126.4±59.2 μmol/L versus 108.7±45.1 μmol/L, P = 0.09). Contrast media use was distributed evenly. Both, 30-day mortality (29% versus 7%, P < 0.0001) and long-term mortality (43% versus 18%, P < 0.0001) were higher; hospital stay was longer in AKI pts (20±12 versus 15±10 days, P = 0.03). Predicted renal failure calculated STS Score was similar (8.0±5.0% [AKI] versus 7.1±4.0% [non-AKI], P = 0.32) and estimated lower renal failure rates than observed. Conclusion. AKI remains a frequent complication with increased mortality in TAVI pts. Careful identification of risk factors and development of more suitable risk scores are essential.
AU  - Gebauer, Katrin
AU  - Diller, Gerhard-Paul
AU  - Kaleschke, Gerrit Tobias
AU  - Kerckhoff, Gregor
AU  - Malyar, Nasser
AU  - Meyborg, Matthias John-Philipp
AU  - Reinecke, Holger
AU  - Baumgartner, Helmut
DA  - 2012
DO  - 10.1155/2012/483748
LA  - eng
N1  - Finanziert durch den Open-Access-Publikationsfonds 2012/2013 der Deutschen Forschungsgemeinschaft (DFG) und der Westfälischen Wilhelms-Universität Münster (WWU Münster).
N1  - International Journal of Nephrology 2012 (2012) 483748
PY  - 2012
TI  - The Risk of Acute Kidney Injury and Its Impact on 30-Day and Long-Term Mortality after Transcatheter Aortic Valve Implantation
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-27379424985
Y2  - 2024-11-22T01:44:18
ER  -