TY  - JOUR
AB  - Mutation rate and effective population size (Ne) jointly determine intraspecific genetic diversity, but the role of mutation rate is often ignored. Here we investigate genetic diversity, spontaneous mutation rate and Ne in the giant duckweed (Spirodela polyrhiza). Despite its large census population size, whole-genome sequencing of 68 globally sampled individuals reveals extremely low intraspecific genetic diversity. Assessed under natural conditions, the genome-wide spontaneous mutation rate is at least seven times lower than estimates made for other multicellular eukaryotes, whereas Ne is large. These results demonstrate that low genetic diversity can be associated with large-Ne species, where selection can reduce mutation rates to very low levels. This study also highlights that accurate estimates of mutation rate can help to explain seemingly unexpected patterns of genome-wide variation.
AU  - Xu, Shuqing
AU  - Stapley, Jessica
AU  - Gablenz, Saskia
AU  - Boyer, Justin
AU  - Appenroth, Klaus-Jürgen
AU  - Sree, K. Sowjanya
AU  - Gershenzon, Jonathan
AU  - Widmer, Alex
AU  - Huber, Meret
DA  - 2019-03-18
DO  - 10.1038/s41467-019-09235-5
KW  - Evolutionary genetics
KW  - Genetic variation
KW  - Genomics
KW  - Plant genetics
LA  - eng
N1  - Nature Communications 10 (2019) 1243, 1-6
N1  - Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster).
PY  - 2019-03-18
TI  - Low genetic variation is associated with low mutation rate in the giant duckweed
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-52129406459
Y2  - 2024-11-22T00:04:59
ER  -