TY  - JOUR
AB  - Albumin is known for its aggregation. As it is a major component of serum, it may be largely responsible for the difficulties in re-suspending dried serum proteins. We found it necessary to break up the solid pellet using a ball mill and subsequently a chaotropic agent and an organic solvent to generate a homogenous protein solution suitable for mass spectrometry-based protein expression analysis.
AU  - Aziz, Shahid
AU  - Zahra, Rabaab
AU  - Berg, Anna Maria
AU  - Ackermann, Doreen
AU  - Rasheed, Faisal
AU  - König, Simone
DA  - 2021
KW  - Albumins
KW  - Serum
KW  - Chaotrop
KW  - Aggregation
KW  - Flüssigkristalle
KW  - Albumin
KW  - serum
KW  - chaotropic agent
KW  - aggregation
KW  - liquid crystals
LA  - eng
IS  - Mercator Journal of Biomolecular Analysis
M2  - 1
N1  - This investigation was part of a research study financially supported by the Pakistan Science Foundation (project # PSF/res/C-PINSTECH/Med (497)) and a fellowship from the International Research Support Initiative Program, Higher Education Commission, Pakistan, for SA.
PY  - 2021
SP  - 1-3
T2  - Mercator Journal of Biomolecular Analysis
TI  - Albumin aggregation and the re-solubilization of dried serum proteins
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-36059704190
Y2  - 2024-11-24T05:36:25
ER  -