TY - JOUR AB - We present multi-color imaging by stimulated Raman scattering (SRS) enabled by an ultrafast fiber-based light source with integrated amplitude modulation and frame-to-frame wavelength tuning. With a relative intensity noise level of -153.7 dBc/Hz at 20.25 MHz the light source is well suited for SRS imaging and outperforms other fiber-based light source concepts for SRS imaging. The light source is tunable in under 5 ms per arbitrary wavelength step between 700 cm−1 and 3200 cm−1, which allows for addressing Raman resonances from the fingerprint to the CH-stretch region. Moreover, the compact and environmentally stable system is predestined for fast multi-color assessments of medical or rapidly evolving samples with high chemical specificity, paving the way for diagnostics and sensing outside of specialized laser laboratories. AU - Würthwein, Thomas AU - Wallmeier, Kristin AU - Brinkmann, Maximilian AU - Hellwig, Tim AU - Lüpken, Niklas M. AU - Lemberger, Nick S. AU - Fallnich, Carsten AU - Fallnich, C. DA - 2021-09-13 DO - 10.1364/BOE.436299 LA - eng N1 - Biomedical Optics Express 12 (2021) 10, 6228-6236 N1 - Real-time imaging of the dDMSO (2125 cm^(-1)) and lipid (2850 cm^(-1)) resonances with stimulated Raman scattering with frame-to-frame wavenumber-switching (256x256 pixels, no averaging) available at https://doi.org/10.6084/m9.figshare.14939160.v1. PY - 2021-09-13 TI - Multi-color stimulated Raman scattering with a frame-to-frame wavelength-tunable fiber-based light source UR - https://nbn-resolving.org/urn:nbn:de:hbz:6-96029549100 Y2 - 2024-11-22T04:37:21 ER -