TY - JOUR AB - Compared with healthy older adults, patients with Alzheimer's disease show decreased alpha and beta power as well as increased delta and theta power during resting state electroencephalography (rsEEG). Findings for mild cognitive impairment (MCI), a stage of increased risk of conversion to dementia, are less conclusive. Cognitive status of 213 non-demented high-agers (mean age, 82.5 years) was classified according to a neuropsychological screening and a cognitive test battery. RsEEG was measured with eyes closed and open, and absolute power in delta, theta, alpha, and beta bands were calculated for nine regions. Results indicate no rsEEG power differences between healthy individuals and those with MCI. There were also no differences present between groups in EEG reactivity, the change in power from eyes closed to eyes open, or the topographical pattern of each frequency band. Overall, EEG reactivity was preserved in 80+-year-olds without dementia, and topographical patterns were described for each frequency band. The application of rsEEG power as a marker for the early detection of dementia might be less conclusive for high-agers. AU - Fröhlich, Stephanie AU - Kutz, Dieter Friedhelm AU - Müller, Katrin AU - Voelcker-Rehage, Claudia DA - 2021-08-11 KW - aged 80 and over KW - EEG reactivity KW - resting state EEG KW - eyes open KW - eyes closed KW - mild cognitive impairment LA - eng N1 - Frontiers in Aging Neuroscience 13 (2021) 675689, 1-14 N1 - Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster). N1 - Förderer: Development Bank of Saxony / Projektnummer: Grant No. 100310502 N1 - Funding organisation: Development Bank of Saxony / Project number: Grant No. 100310502 PY - 2021-08-11 TI - Characteristics of Resting State EEG Power in 80+-Year-Olds of Different Cognitive Status UR - https://nbn-resolving.org/urn:nbn:de:hbz:6-85089672102 Y2 - 2024-11-21T19:44:44 ER -