TY  - JOUR
AB  - Chronic nodular prurigo presents with multiple pruriginous nodules and severe pruritus. This study aims to explore the treatment course and regimens in patients with chronic nodular prurigo and to analyse predictive factors contributing to therapeutic success. A total of 325 patients with chronic nodular prurigo (male 37.5%) were analysed concerning demographic data, pruritus intensity, medical history, psychological impairment, quality of life, treatment duration, regimens and outcome. These parameters were compared with 325 sex- and age-matched patients with chronic pruritus on non-lesional skin. Treatment success was dependent on duration and regime of treatment and independent of age, sex and initial itch intensity. Non-responders displayed a higher percentage of inflamed nodules, a higher portion of excoriated nodules and a higher impairment of quality of life and mood factors before initiation of treatment. Gabapentinoids and immunosuppressants proved to be the most successful therapeutic agents. Compared with patients with chronic pruritus, those with chronic nodular prurigo needed longer duration of therapy.
AU  - Gründel, Sonja Olivia
AU  - Krettek, Sonja Olivia
AU  - Pereira, Manuel P.
AU  - Storck, Michael
AU  - Storck, Michael Martin
AU  - Osada, Nani
AU  - Schneider, Gudrun
AU  - Ständer, Sonja
AU  - Zeidler, Claudia
DA  - 2020-06-17
DO  - 10.17879/64049595893
KW  - anti­pruritic therapy
KW  - chronic prurigo
KW  - pruritus
KW  - treatment
KW  - prurigo nodularis
LA  - eng
N1  - Acta Dermato- Venereologica 100 (2020) adv00269, 1-7
N1  - Finanziert durch den Open-Access-Publikationsfonds der Westfälischen Wilhelms-Universität Münster (WWU Münster)
PY  - 2020-06-17
TI  - Analysis of 325 Patients with Chronic Nodular Prurigo: Clinics, Burden of Disease and Course of Treatment
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-64049587978
Y2  - 2024-11-22T04:28:11
ER  -