TY  - JOUR
AB  - Background: Sarcoidosis is a multisystem granulomatous disease of not sufficiently understood origin. Some patients develop cardiac involvement in course of the disease which is mostly responsible for adverse outcome. In addition to complications like high degree atrioventricular (AV) block or ventricular tachyarrhythmias, there is a certain percentage of patients developing atrial tachyarrhythmias. Data is limited and the role of catheter ablation uncertain. Therefore, we studied sarcoid patients who presented with supraventricular tachyarrhythmias. Hypothesis: Treatment and ablation of supraventricular tachycardia could be hampered by inflammation in patients with cardiac sarcoidosis. Methods: We enrolled 37 consecutive patients with cardiac sarcoidosis who presented with atrial tachyarrhythmias and underwent an electrophysiologic study over a period of 6 years (03/2013-04/2019). In total, 16 catheter ablations for atrial tachyarrhythmias were performed. Mean follow-up duration was 2.5 years. Results: Most common ablation performed was cavo-tricuspid isthmus ablation for typical atrial flutter in seven patients (54%). Pulmonary vein isolation for treatment of atrial fibrillation (AF) was performed in five patients (38%). Two patients received slow-pathway modulation for treatment of recurrent atrioventricular nodal reentry tachycardia (AVNRT). All but two patients with AF had no clinical recurrence during follow-up. Two patients had recurrence of AF but still reported markedly improved european heart rhythm association (EHRA) class. Periprocedural safety was very high. There were no adverse events related to the ablation procedure. One patient died during follow-up in the presence of electrical storm. Conclusion: Catheter ablations of supraventricular tachycardias seem to be safe and effective in patients with cardiac sarcoidosis. Outcome is comparable to patients without inflammatory heart disease, although data from larger patient collectives are mandatory to make recommendations in this special entity.
AU  - Willy, Kevin Kurt
AU  - Dechering, Dirk G.
AU  - Wasmer, Kristina
AU  - Köbe, Julia
AU  - Bögeholz, Nils
AU  - Ellermann, Christian
AU  - Leitz, Patrick R.
AU  - Reinke, Florian Johann
AU  - Frommeyer, Gerrit
AU  - Eckardt, Lars
DA  - 2019-09-03
DO  - 10.17879/53089481691
KW  - cardiac sarcoidosis
KW  - catheter ablation
KW  - inflammatory heart disease
KW  - sarcoidosis
LA  - eng
N1  - Clinical Cardiology 42 (2019) 11, 1121-1125
N1  - Finanziert über die DEAL-Vereinbarung mit Wiley 2019-2022.
PY  - 2019-09-03
TI  - Outcome of catheter ablation of supraventricular tachyarrhythmias in cardiac sarcoidosis
UR  - https://nbn-resolving.org/urn:nbn:de:hbz:6-23089733168
Y2  - 2024-11-22T00:22:01
ER  -