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Kuhl, Ulrike: The brain basis of emerging literacy and numeracy skills. Longitudinal neuroimaging evidence from kindergarten to primary school. 2019
Inhalt
Acknowledgements
Contents
List of figures
List of Tables
List of Acronyms
1 Introduction
2 Literacy and Numeracy
2.1 Foundations of literacy
2.1.1 The brain basis of literacy
2.1.2 Developmental dyslexia
2.1.2.1 Cognitive deficits and neurobiological theories
2.1.2.2 Disentangling potential causes from consequences of developmental dyslexia
2.2 Foundations of numeracy
2.2.1 The brain basis of numeracy
2.3 Potential links between literacy and numeracy
2.4 Studying literacy and numeracy: prominent confounds
3 Research aims and hypotheses
3.1 Empirical study I
3.2 Empirical study II
4 Brain structural and functional development
4.1 General brain structure
4.2 Microanatomical brain development
4.3 Macroanatomical brain development
4.4 Functional brain development
5 Examining brain structure and function via magnetic resonance imaging
5.1 Magnetic resonance imaging
5.1.1 Basic principles of magnetic resonance imaging measurements
5.1.2 Parameters determining image contrast
5.2 Functional magnetic resonance imaging
5.3 Examining grey matter structure
5.3.1 Voxel-based morphometry
5.3.2 Surface-based morphometry
5.3.2.1 Cortical thickness
5.3.2.2 Gyrification index and cortical folding complexity
5.3.2.3 Sulcus depth
5.4 Examining white matter structure
5.4.1 Diffusion–weighted magnetic resonance imaging
5.4.1.1 The diffusion tensor
5.4.1.2 Probabilistic tractography and streamline density
5.5 Examining functional coherence of neural systems
5.5.1 Resting state functional connectivity
5.5.2 Regional homogeneity
5.5.3 Fractional amplitude of low frequency fluctuations
5.6 Statistical analysis
6 Empirical Study I: Unraveling potential causes from consequences of developmental dyslexia
6.1 Introduction
6.2 Methods
6.2.1 Participants
6.2.2 Behavioral cognitive assessment and sociodemographic status
6.2.3 Magnetic resonance imaging data acquisition
6.2.4 Magnetic resonance imaging data preprocessing
6.2.5 Voxel–based and surface–based morphometry
6.2.6 Regions of interest selection
6.2.7 Tractography
6.2.8 Functional coherence measures
6.2.9 Statistical analysis
6.3 Results
6.4 Discussion
7 Empirical Study II: Surface plasticity and numeracy skills
7.1 Introduction
7.2 Methods
7.2.1 Participants
7.2.2 Behavioral cognitive assessment and sociodemographic status
7.2.3 Magnetic resonance imaging data acquisition
7.2.4 Magnetic resonance imaging data preprocessing
7.2.5 Surface based morphometry
7.2.6 Statistical analysis
7.3 Results
7.4 Discussion
8 General Discussion
8.1 Summary of results
8.2 Integrating current findings with theories of dyslexia
8.3 Integrating current findings with theories of numeracy development
8.4 Concluding remarks
Bibliography
Curriculum Vitae
Publications & Talks
Summary of dissertation
Zusammenfassung der Dissertation
Declaration