Corynebacterium glutamicum is used for the million-ton-scale production of amino

acids. Valorization of sidestreams from agri- and aqua-culture has focused on the

production of biofuels and carboxylic acids. Nitrogen present in various amounts in

sidestreams may be valuable for the production of amines, amino acids and other

nitrogenous compounds. Metabolic engineering of C. glutamicum for valorization of

agri- and aqua-culture sidestreams addresses to bridge this gap. The product portfolio

accessible via C. glutamicum fermentation primarily features amino acids and diamines

for large-volume markets in addition to various specialty amines. On the one hand, this

review covers metabolic engineering of C. glutamicum to efficiently utilize components

of various sidestreams. On the other hand, examples of the design and implementation

of synthetic pathways not present in native metabolism to produce sought after

nitrogenous compounds will be provided. Perspectives and challenges of this concept

will be discussed