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Heidemann, Stephanie Claudia: Role of the TL1A/DR3 pathway in NK cell effector functions. 2008
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Table of contents
3.2 Culture of tumor cell lines……………………………………………… 22
3.3 Flow cytometric analysis……………………………………………….. 23
List of figures
List of tables
List of abbreviations
1 Introduction
2 Materials
2.3 Cytokines
2.4 Antibodies
3 Methods
3.2 Culture of tumor cell lines
3.3 Flow cytometric analysis
3.4 Detection of IFN-( by ELISA
3.5 51Cr-release assay
3.7 Statistical analysis
4 Results
Figure 4.9: Effect of TL1A on IL-12/IL-18 induced cytotoxicity of PBMC tested against cell lines lysed only by activated NK cells. PBMC were cultured and tested for their cytotoxicity against the NK-resistant target cells Daudi (n=7), WiDr (n=3) and SW837 (n=3) in 51Cr-release assays (left upper panel and lower panels) and compared to the cytotoxicity toward K562 cells (right upper panel). The results are shown in LU30/107 effector cells. Cytotoxicity of IL-12/IL-18 and TL1A treated NK cells toward Daudi ce
5 Discussion
6 Abstract
7 References
8 Acknowledgments
9 Curriculum vitae
9 Curriculum vitae
Personal details
Name: Stephanie Claudia Heidemann
Education
Higher Education
Nov 2005 “Dritter Abschnitt der Ärztlichen Prüfung” (Third Section of the Medical Examination), hereby obtaining the M.D. Degree
Dec 2005 “Approbation als Ärztin” (License to practice medicine)
10 Lebenslauf
10 Lebenslauf
Persönliche Daten
Name: Stephanie Claudia Heidemann
Schulbildung
Hochschulbildung
Nov 2005 Dritter Abschnitt der Ärztlichen Prüfung
Dez 2005 Approbation als Ärztin