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Lemke, Dorothea; Kirchner, Dorothea; Mattauch, Volkmar Robert; Heidinger, Oliver; Pebesma, Edzer J.; Hense, Hans-Werner: Detecting cancer clusters in a regional population with local cluster tests and Bayesian smoothing methods: a simulation study
Inhalt
Background
Data and methods
Study area
Simulation design
Local cluster tests
- Local Moran’s I
- Kulldorff’s spatial scan statistic
- Approach of Besag & Newell
Bayesian smoothing methods
- Empirical Bayes smoothing
- Hierarchical Bayes smoothing (BYM model)
Evaluation of the simulation results
Results
Results of the simulation process
Results of the local cluster tests
Results of the Bayesian smoothing methods
Discussion
Local cluster tests
Bayesian smoothing methods
Strengths and limitations
Summary and conclusion
Competing interests
Authors’ contributions
Acknowledgement
Author details
References